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Anti-Mouse NK1.1 Antibody, PE-Cy7
Catalog #: 135-23038
Mouse NK1.1 Antibody [clone: PK136], monoclonal rat IgG2a kappa. Validated for flow cytometry.
Product Description
Specifications
| Size | 25 µg, 100 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Mouse |
| Host Species | Rat |
| Accession Number | Q0ZUP1 |
| Gene Id | 100043861 |
| Gene Symbols | Klrb1, Gm4696, Klrb1d, Klrb1g, Klrb6, Nkrp1g |
| Protein Name / Synonyms | Killer cell lectin-like receptor subfamily B member 1 (Killer cell lectin-like receptor subfamily B member 1G) (Natural killer cell surface protein NKR-P1G) (Natural killer lectin-like receptor 1E) |
| Clonality | Monoclonal |
| Clone | PK136 |
| Conjugation | PE-Cy7 |
| Preparation | The antibody was purified by affinity chromatography. |
| Isotype | IgG2a Kappa |
| Format | Liquid |
| Concentration (lot specific) | 0.5 mg/ml |
| Buffers | PBS, pH 7.2-7.4, 0.2% BSA, 0.1% sodium azide |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease |
| Excitation Laser | Green Laser, 565 nm |
| Maximum Emission Wavelength | 778 nm |
| Shipping Type | Blue ice |
| Storage | 4°C |
Description
Product Features
- Serum-free media used for cell culture of hybridomas to minimize bovine antibody contamination
- Gentle elution at pH 4.0 to minimize antibody degradation
- Protein A, G & L affinity purification
- High purity
Description
NK1.1 surface antigen is encoded by the NKR-P1B/NKR-P1C gene. Also named KLRB1 protein, NKR-P1A or CD161 is classified as a type II membrane protein. NK1.1 is expressed by natural killer cells and a subset of T cells in the mouse strains C57BL/6, FVB/N, and NZB but is not present in the mouse strains AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. NK cells play an important role in anti-tumor immunity and allograft rejection after bone marrow transplantation. Dendritic cells present tumor antigen to NK cells through CD1d molecules.
Recommended Usage
Each lot of antibody has been tested by flow cytometry staining. We suggest use ≤ 0.5 µg per million cells in 100 µl volume of staining buffer. Researchers are recommended to further titrate this antibody at the optimal concentration for each specific application.
Storage / Stability
Store at 2 °C ~ 8 °C, protected from prolonged light exposure. DO NOT FREEZE.