Anti-Mouse OLR1 Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	P78380
Gene Id	4973
Gene Symbols	OLR1
Protein Name / Synonyms	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, oxidized low-density lipoprotein receptor 1
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Dilutions

WB 1:500 - 1:1000

Format

Calculated MW

20kDa/21kDa/30kDa

Observed MW

31kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OLR1 (NP_002534.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of mouse lung, using OLR1 antibody (144-012060) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Western blot - OLR1 antibody (144-012060)

Expiration:

12 months from the date of shipment when stored properly.

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