Anti-Mouse p27Kip1 (C-term T197) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	P46414
Gene Id	12576
Gene Symbols	CDKN1B
Protein Name / Synonyms	p27Kip1 (C-term T197)
Clonality	Polyclonal
Preparation	This Mouse p27Kip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-197 amino acids from the C-terminal region of mouse p27Kip1.
Concentration (lot specific)	0.280 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of cyclin D-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Specificity

Other Names

Cdkn1b;Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor 1B; p27Kip1

NCBI Accession #

NP_034005.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22193

Recommended Dilutions

WB: 1:1000

Mouse p27Kip1 Antibody (C-term T197) (Cat# 102-14659) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the (mouse) p27Kip1 antibody detected the (mouse) p27Kip1 protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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