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Anti-Mouse RASAL1 (Center) Antibody

Catalog #: 102-11579

Rabbit Anti-Mouse RASAL1 (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesMouse
Host SpeciesRabbit
Accession Number
O95294
Gene Id
8437
Gene Symbols
RASAL1
Protein Name / Synonyms
RASAL1 (Center)
ClonalityPolyclonal
PreparationThis RASAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described

Specificity

Other Names
RASAL1; RASAL; RasGAP-activating-like protein 1
NCBI Accession #
NP_001180449.1;NP_001180450.1;NP_004649.2
Other Accession #
NP_004649.2; NP_001180450.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
90016
Recommended Dilutions
WB: 1:1000
RASAL1 Antibody (Center) (Cat# 102-11579) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the RASAL1 antibody detected the RASAL1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.