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Anti-Mouse Shh (C-term) Antibody
Catalog #: 102-24277
Rabbit Anti-(Mouse) Shh (C-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q62226 |
| Gene Id | 20423 |
| Gene Symbols | Shh |
| Protein Name / Synonyms | Sonic hedgehog protein, SHH, HHG-1, Sonic hedgehog protein N-product, Sonic hedgehog protein 19 kDa product, Sonic hedgehog protein C-product, Sonic hedgehog protein 27 kDa product, Shh, Hhg1 |
| Clonality | Polyclonal |
| Clone | RB51214 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, FC |
| Research Area | Angiogenesis, Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity).
Other Information
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
47773
Antigen Source
Human
Images
FC (1:25)
Flow cytometric analysis of Hela cells using (Mouse) Shh Antibody (C-term)(green, Cat#102-24277) compared to an isotype control of rabbit IgG(blue). 102-24277 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.