Anti-Mouse TIGAR (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	Q9NQ88
Gene Id	57103
Gene Symbols	TIGAR
Protein Name / Synonyms	TIGAR (N-term)
Clonality	Polyclonal
Preparation	This TIGAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TIGAR.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq].

Specificity

Other Names

TIGAR; C12orf5; Fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator

NCBI Accession #

NP_065108.1

Other Accession #

NP_065108.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

30063

Recommended Dilutions

WB: 1:1000

TIGAR Antibody (N-term) (Cat# 102-14179) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TIGAR antibody detected the TIGAR protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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