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Anti-Mouse TLR8 (C-term) Antibody
Catalog #: 102-12778
Rabbit Anti-Mouse TLR8 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P58682 |
| Gene Id | 170744 |
| Gene Symbols | TLR8 |
| Protein Name / Synonyms | TLR8 (C-term) |
| Clonality | Polyclonal |
| Preparation | This Mouse TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-987 amino acids from the C-terminal region of mouse TLR8. |
| Concentration (lot specific) | 0.460 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR8 is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Specificity
Other Names
Tlr8; Toll-like receptor 8; CD_antigen=CD288; Flags: Precursor
NCBI Accession #
NP_573475.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
119358
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | TLR8 Antibody (E972) (Cat# 102-12778) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TLR8 antibody detected the TLR8 protein (arrow). |
 | Mouse TLR8 Antibody (C-term) (Cat# 102-12778)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse TLR8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.