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Anti-Muscle Actin Antibody

Catalog #: 188-11422

Mouse anti-Human/Rat Muscle Actin Antibody

Product Description

Specifications

Size20 µg, 100 µg
Estimated Lead Time1-2 weeks
SpeciesHuman, Rat
Specificity
Other species not tested.
Host SpeciesMouse
Accession Number
P62736
Gene Id
59
Gene Symbols
ACTA2,ACTSA,ACTVS,GIG46
Protein Name / Synonyms
Actin, aortic smooth muscle (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein)
Immunogen
An amino acid sequence common among human muscle actins was used as the immunogen for the Muscle Actin antibody.
IsotypeKappa, IgG1
Purity
Protein G affinity chromatography
Concentration (lot specific)
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Recommended Applications
Western blot: 0.5-1ug/ml
Immunofluorescence: 1-2ug/ml
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Domain / Region / TerminusCytoplasmic
Research AreaCytoskeletal Reorganization
Shipping TypeBlue ice
Storage≤-20°C

Description

Description

Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. An actin protein's mass is roughly 42-kDa and it is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division. [Wiki]

This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells.

Storage

Store the Muscle Actin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.