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Anti-MXI1 (Center) Antibody
Catalog #: 102-12753
Rabbit Anti-Mouse MXI1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P50539 |
| Gene Id | 4601 |
| Gene Symbols | MXI1 |
| Protein Name / Synonyms | MXI1 (Center) |
| Clonality | Polyclonal |
| Preparation | This MXI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of human MXI1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Specificity
Predicted Reactivity
Rat
Other Names
MXI1; BHLHC11; Max-interacting protein 1; Class C basic helix-loop-helix protein 11
NCBI Accession #
NP_001008541.1;NP_005953.4;NP_569157.2
Other Accession #
O09015; P50540; NP_005953.4; NP_569157.2; NP_001008541.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
26062
Recommended Dilutions
WB: 1:1000
 | MXI1 Antibody (Center) (Cat# 102-12753) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MXI1 antibody detected the MXI1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.