Anti-NACC2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96BF6\|NP_653254.1
Gene Symbols	NACC2
Protein Name / Synonyms	Nucleus accumbens-associated protein 2, NAC-2, BTB/POZ domain-containing protein 14A, Repressor with BTB domain and BEN domain, NACC2, BTBD14A, NAC2, RBB
Clonality	Polyclonal
Clone	RB36237
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.

Other Information

NCBI Accession #

NP_653254.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Antigen Source

Human

Images

WB (1:1000)

NACC2 Antibody (C-term) (Cat. #102-22419) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NACC2 antibody detected the NACC2 protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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