Anti-NAE1 (APPBP1) (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q13564\|Q9Z1A5\|Q8VBW6\|Q4R3L6\|NP_003896
Gene Id	8883
Gene Symbols	NAE1
Protein Name / Synonyms	NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Clonality	Polyclonal
Clone	RB14670
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

APPBP1 binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPBP1 is required for cell cycle progression through the S/M checkpoint.

Other Information

NCBI Accession #

NP_001018169.1;NP_001018170.1;NP_003896.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Calculated Molecular Weight (Da)

60246

Antigen Source

Human

Images

WB (1:1000)

Western blot analysis of APPBP1 (arrow) using rabbit polyclonal APPBP1 Antibody (C-term) (Cat.#102-27229).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the APPBP1 gene (Lane 2) (Origene Technologies).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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