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Anti-NBN (C-term) Antibody
Catalog #: 102-11249
Rabbit Anti-Human NBN (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O60934 |
| Gene Id | 4683 |
| Gene Symbols | NBN |
| Protein Name / Synonyms | NBN (C-term) |
| Clonality | Polyclonal |
| Preparation | This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN. |
| Concentration (lot specific) | 0.270 mg/ml |
| Recommended Applications | Western Blotting, IF, FC |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Specificity
Other Names
NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1
NCBI Accession #
NP_002476.2
Other Accession #
NP_002476.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
84959
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; FC: 1:10-50
 | NBN Antibody (C-term) (Cat# 102-11249) western blot analysis in NCI-H460,NCI-H292 cell line lysates (35ug/lane).This demonstrates the NBN antibody detected the NBN protein (arrow). |
 | Confocal immunofluorescent analysis of NBN Antibody (C-term) (Cat# 102-11249) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | NBN Antibody (C-term) (Cat# 102-11249) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.