Anti-NDUFS8 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O00217
Gene Id	4728
Gene Symbols	NDUFS8
Protein Name / Synonyms	NDUFS8 (Center)
Clonality	Polyclonal
Preparation	This NDUFS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human NDUFS8.
Concentration (lot specific)	0.480 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Specificity

Predicted Reactivity

Mouse, Bovine, C.Elegans, Monkey

Other Names

NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Complex I-23kD; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY subunit

NCBI Accession #

NP_002487.1

Other Accession #

Q8K3J1; Q60HE3; Q22619; P42028; NP_002487.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

23705

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	NDUFS8 Antibody (Center) (Cat# 102-11626) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NDUFS8 antibody detected the NDUFS8 protein (arrow).
	NDUFS8 Antibody (Center) (Cat# 102-11626)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NDUFS8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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