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Anti-NEDD9 (Center) Antibody
Catalog #: 102-12562
Rabbit Anti-Human NEDD9 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q14511 |
| Gene Id | 4739 |
| Gene Symbols | NEDD9 |
| Protein Name / Synonyms | NEDD9 (Center) |
| Clonality | Polyclonal |
| Preparation | This NEDD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-363 amino acids from the Central region of human NEDD9. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B-and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.
Specificity
Other Names
NEDD9; CASL; CASS2; Enhancer of filamentation 1; CRK-associated substrate-related protein; Cas scaffolding protein family member 2; Neural precursor cell expressed developmentally down-regulated protein 9; Renal carcinoma antigen NY-REN-12; p105; Enhancer of filamentation 1 p55
NCBI Accession #
NP_001135865.1;NP_001257962.1;NP_006394.1;NP_892011.2
Other Accession #
NP_006394.1; NP_892011.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
92861
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | NEDD9 Antibody (Center) (Cat# 102-12562) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the NEDD9 antibody detected the NEDD9 protein (arrow). |
 | NEDD9 Antibody (Center) (102-12562)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NEDD9 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.