Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

WB 1:500 - 1:2000; IF 1:50 - 1:200

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NEFM (NP_005373.2).

Unmodified

Store at -20°. Avoid freeze / thaw cycles.