Anti-NFATC1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O95644
Gene Id	4772
Gene Symbols	NFATC1
Protein Name / Synonyms	NFATC1 (C-term)
Clonality	Polyclonal
Preparation	This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 amino acids from the C-terminal region of human NFATC1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Specificity

Other Names

NFATC1; NFAT2; NFATC; Nuclear factor of activated T-cells, cytoplasmic 1; NFAT transcription complex cytosolic component

NCBI Accession #

NP_001265598.1;NP_001265599.1;NP_001265601.1;NP_001265602.1;NP_001265604.1;NP_006153.2;NP_765975.1;NP_765976.1;NP_765977.1;NP_765978.1

Other Accession #

NP_765977.1; NP_765978.1; NP_765975.1; NP_006153.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

101243

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	NFATC1 Antibody (C-term) (Cat# 102-12211) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NFATC1 antibody detected the NFATC1 protein (arrow).
	NFATC1 Antibody (C-term) (102-12211)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NFATC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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