Anti-NM23 (NME1) (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15531
Gene Id	4830
Gene Symbols	NME1
Protein Name / Synonyms	NM23 (NME1) (N-term)
Clonality	Polyclonal
Preparation	This NM23 (NME1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human NM23 (NME1).
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IF, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. NME1 encodes the 'A' isoform of nucleoside diphosphate kinase (NDK). NDK exists as a hexamer composed of the 'A' (NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas.

Specificity

Other Names

NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; Granzyme A-activated DNase; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1

NCBI Accession #

NP_000260.1;NP_937818.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

17149

Recommended Dilutions

WB: 1:1000; IF: 1:10-50; IHC: 1:50-100

	NME1 Antibody (F40) (Cat# 102-17789) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NME1 antibody detected the NME1 protein (arrow).
	Confocal immunofluorescent analysis of NM23 (NME1) Antibody (N-term)(Cat# 102-17789) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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