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Anti-NOD2 Antibody
Catalog #: 144-64013
NOD2 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q9HC29 |
| Gene Id | 64127 |
| Gene Symbols | NOD2 |
| Protein Name / Synonyms | NOD2, ACUG, BLAU, BLAUS, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1, YAOS, nucleotide binding oligomerization domain containing 2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Cancer, Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
22kDa/112kDa/115kDa
Observed MW
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 611-910 of human NOD2 (NP_071445.1).
Modification
Storage
Store at -20°. Avoid freeze / thaw cycles.
Expiration:
12 months from the date of shipment when stored properly.