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Anti-NOTCH4 (C-term) Antibody
Catalog #: 102-24595
Rabbit Anti-NOTCH4 (C-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q99466 |
| Gene Id | 4855 |
| Gene Symbols | NOTCH4 |
| Protein Name / Synonyms | Neurogenic locus notch homolog protein 4, Notch 4, hNotch4, Notch 4 extracellular truncation, Notch 4 intracellular domain, NOTCH4, INT3 |
| Clonality | Polyclonal |
| Clone | RB52895 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
Other Information
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
209622
Antigen Source
Human
Images
WB (1:2000)
Anti-NOTCH4 Antibody (C-term)at 1:2000 dilution + human liver lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 210 kDa (isoform-1) and 62Kda(isoform-2) Blocking/Dilution buffer: 5% NFDM/TBST.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.