Anti-NPPA Antibody

Product Description

Specifications

Size	20 µL, 100 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse, Rat
Host Species	Rabbit
Accession Number	P01160
Gene Id	4878
Gene Symbols	NPPA
Protein Name / Synonyms	NPPA, ANF, ANP, ATFB6, ATRST2, CDD, CDD-ANF, CDP, PND, natriuretic peptide A
Clonality	Polyclonal
Isotype	IgG
Purity	Affinity purification
Concentration (lot specific)	3.98 mg/ml
Buffers	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended Applications	Western Blotting, IF
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Background

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Dilutions

WB 1:500 - 1:2000
IF 1:10 - 1:100

Format

Calculated MW

16kDa

Observed MW

16kDa

Immunogen

Recombinant protein of human NPPA

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using NPPA antibody (144-01609) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
Western blot - NPPA Polyclonal Antibody (144-01609)