Anti-NTAN1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96AB6
Gene Id	123803
Gene Symbols	NTAN1
Protein Name / Synonyms	NTAN1 (C-term)
Clonality	Polyclonal
Preparation	This NTAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human NTAN1.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position (By similarity).

Specificity

Other Names

NTAN1; Protein N-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine deamidase

NCBI Accession #

NP_001257695.1;NP_001257696.1;NP_775745.1

Other Accession #

NP_775745.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

34677

Recommended Dilutions

WB: 1:1000

NTAN1 Antibody (C-term) (Cat# 102-13529) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the NTAN1 antibody detected the NTAN1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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