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Anti-ORC2L (Center) Antibody
Catalog #: 102-12510
Rabbit Anti-Human ORC2L (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q13416 |
| Gene Id | 4999 |
| Gene Symbols | ORC2 |
| Protein Name / Synonyms | ORC2L (Center) |
| Clonality | Polyclonal |
| Preparation | This ORC2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human ORC2L. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.
Specificity
Other Names
ORC2; ORC2L; Origin recognition complex subunit 2
NCBI Accession #
NP_006181.1
Other Accession #
NP_006181.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
65972
Recommended Dilutions
WB: 1:1000
 | ORC2L Antibody (Center) (Cat# 102-12510) western blot analysis in HUVEC cell line lysates (35ug/lane).This demonstrates the ORC2L antibody detected the ORC2L protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.