Anti-OSCAR (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8IYS5
Gene Id	126014
Gene Symbols	OSCAR
Protein Name / Synonyms	OSCAR (C-term)
Clonality	Polyclonal
Preparation	This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

OSCAR; Osteoclast-associated immunoglobulin-like receptor; Polymeric immunoglobulin receptor 3

NCBI Accession #

NP_001269278.1;NP_001269279.1;NP_570127.3;NP_573398.2;NP_573399.2;NP_996554.2

Other Accession #

NP_570127.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

30481

Recommended Dilutions

WB: 1:1000

OSCAR Antibody (C-term)(Cat# 102-14031) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the OSCAR antibody detected the OSCAR protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products