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Anti-P-Cadherin / CDH3 Antibody, Sodium Azide Free
Catalog #: 188-11161-SAF
Mouse anti-Human P-Cadherin Antibody / CDH3 [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | P22223 |
| Gene Id | 1001 |
| Gene Symbols | CDH3,CDHP |
| Protein Name / Synonyms | Cadherin-3 (Placental cadherin) (P-cadherin) |
| Immunogen | Membrane from trypsinized A431 cells was used as the immunogen for this P-Cadherin antibody. |
| Isotype | Kappa, IgG1 |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | IF: 1-2ug/ml Western Blotting: 1-2ug/mll |
| Domain / Region / Terminus | Cell surface, cytoplasmic |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
Recognizes a protein of 116kDa, identified as P-Cadherin, or Cadherin 3 or CDH3. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.
Storage
Store the P-Cadherin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.