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ISO 13485:2016 cGMP
Anti-P-FAK Antibody
Catalog #: 130-10618
Product Description
Specifications
| Size | 20 µg, 100 µg, 200 µg, 500 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q05397 |
| Gene Id | 5747 |
| Gene Symbols | PTK2 FAK FAK1 |
| Protein Name / Synonyms | P-FAK(392-403) |
| Clonality | Polyclonal |
| Immunogen | This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen P-FAK(392-403):CSETDDY(PO3H2)AEEIIDE. This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified by Protein A affinity chromatography. |
| Immunogen Sequence | 392-CSETDDY(PO3H2)AEIIDE-403 aa |
| Concentration (lot specific) | 1 mg/ml |
| Recommended Applications | ELISA (recommended work dilution= 1:32, 000) |
| Reconstitution | Product is supplied as a powder obtained from lyophilization of purified antibody in 1X PBS, aliquot using ddH2O. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml. |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
FAK is an important member of integrin-mediated signal transduction, has tyrosine kinase activity, and can be autophosphorylated; New members of the FAK family, like FAK's role, continue to be discovered. FAK has recently been found to inhibit apoptosis and FAK itself is a substrate for caspase. FAK, as a signal molecule, also has crosstalk with other signal transduction pathways within the cell and is directly involved in the regulation of various functions of cells.
Typical Data
Storage/Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Expiration
12 months from the date of shipment when stored properly.