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Anti-P450R (Center) Antibody
Catalog #: 102-27028
Rabbit Anti-P450R (Center) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P16435 |
| Gene Id | 5447 |
| Gene Symbols | POR |
| Protein Name / Synonyms | NADPH--cytochrome P450 reductase, CPR, P450R, POR, CYPOR |
| Clonality | Polyclonal |
| Clone | RB19543 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Other Information
NCBI Accession #
NP_000932.3
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
76690
Antigen Source
Human
Images
WB (1:1000)
Western blot analysis of P450R antibody (Center) (Cat.# 102-27028) in K562 cell line lysates (35ug/lane). P450R (arrow) was detected using the purified Pab.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.