Anti-PACRG (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96M98
Gene Id	135138
Gene Symbols	PACRG
Protein Name / Synonyms	PACRG (N-term)
Clonality	Polyclonal
Preparation	This PACRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human PACRG.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

PACRG; GLUP; Parkin coregulated gene protein; Molecular chaperone/chaperonin-binding protein; PARK2 coregulated gene protein

NCBI Accession #

NP_001073847.1;NP_001073848.1;NP_689623.2

Other Accession #

NP_001073847.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

33342

Recommended Dilutions

WB: 1:1000

PACRG Antibody (N-term) (Cat# 102-13492) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PACRG antibody detected the PACRG protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products