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Anti-PADI2 (C-term) Antibody
Catalog #: 102-12455
Rabbit Anti-Human PADI2 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9Y2J8 |
| Gene Id | 11240 |
| Gene Symbols | PADI2 |
| Protein Name / Synonyms | PADI2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq].
Specificity
Other Names
PADI2; KIAA0994; PDI2; Protein-arginine deiminase type-2; PAD-H19; Peptidylarginine deiminase II; Protein-arginine deiminase type II
NCBI Accession #
NP_031391.2
Other Accession #
NP_031391.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
75564
Recommended Dilutions
WB: 1:1000
 | PADI2 Antibody (C-term) (Cat# 102-12455) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PADI2 antibody detected the PADI2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.