Anti-PAIP2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9BPZ3
Gene Id	51247
Gene Symbols	PAIP2
Protein Name / Synonyms	PAIP2 (N-term)
Clonality	Polyclonal
Preparation	This PAIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human PAIP2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Specificity

Predicted Reactivity

Bovine, Chicken

Other Names

PAIP2; PAIP2A; Polyadenylate-binding protein-interacting protein 2

NCBI Accession #

NP_001028284.1;NP_057564.3

Other Accession #

Q5ZJS6; Q3ZC67; NP_057564.3; NP_001028284.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

14984

Recommended Dilutions

WB: 1:1000

	PAIP2 Antibody (N-term) (Cat# 102-13131) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PAIP2 antibody detected the PAIP2 protein (arrow).
	Western blot analysis of PAIP2 (arrow) using rabbit polyclonal PAIP2 Antibody (N-term) (Cat# 102-13131). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PAIP2 gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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