PAK1 Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Rat |
| Host Species | Rabbit |
| Accession Number | Q13153 |
| Gene Id | 5058 |
| Gene Symbols | PAK1 |
| Protein Name / Synonyms | PAK1, PAKalpha, p21 (RAC1) activated kinase 1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IHC 1:50 - 1:100
Format
Calculated MW
60kDa/61kDa
Observed MW
Refer to figures
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PAK1 (NP_002567.3).
Modification
Unmodified
Storage
-20°C
Images
Immunohistochemistry of paraffin-embedded rat kidney using PAK1 antibody (144-60034) at dilution of 1:200 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.