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Anti-PCBD1 (Center) Antibody
Catalog #: 102-18145
Rabbit Anti-PCBD1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P61457 |
| Gene Id | 5092 |
| Gene Symbols | PCBD1 |
| Protein Name / Synonyms | PCBD1 (Center) |
| Clonality | Polyclonal |
| Preparation | This PCBD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-37 amino acids from the Central region of human PCBD1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).
Specificity
Predicted Reactivity
Rat, Bovine
Other Names
PCBD1; DCOH; PCBD; Pterin-4-alpha-carbinolamine dehydratase; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase
NCBI Accession #
NP_000272.1
Other Accession #
P61459; Q3ZBD3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
12000
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of PCBD1 Antibody (Center) (Cat# 102-18145) in mouse liver tissue lysates (35ug/lane). PCBD1 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with PCBD1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | PCBD1 Antibody (Center) (Cat# 102-18145) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.