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Anti-PDCD1 / PD-1 Antibody
Catalog #: 188-11472-IHC
Rabbit anti-Human Recombinant PDCD1 / PD-1 Antibody [IHC only]
Product Description
Specifications
| Size | 7 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | Other species not tested. |
| Host Species | Rabbit |
| Accession Number | Q15116 |
| Gene Id | 5133 |
| Gene Symbols | PDCD1,PD1 |
| Protein Name / Synonyms | Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279) |
| Immunogen | A partial length human protein was used as the immunogen for the recombinant PD1 antibody. |
| Isotype | IgG, Kappa |
| Purity | Protein A affinity chromatography |
| Concentration (lot specific) | Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only* |
| Recommended Applications | Prediluted IHC only format: incubate for 30 min at RT (1) |
| Domain / Region / Terminus | Cell surface & cytoplasmic |
| Research Area | Cancer, Autoimmune Disease, Cancer Immunology, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.
Storage
Store the recombinant PD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.