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Anti-PDE4B (Center) Antibody
Catalog #: 102-20912
Rabbit Anti-PDE4B (Center) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q07343|NP_002591.2|NP_001032418.1 |
| Gene Id | 5142 |
| Gene Symbols | PDE4B |
| Protein Name / Synonyms | cAMP-specific 3',5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4B, DPDE4 |
| Clonality | Polyclonal |
| Clone | RB18545 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Information
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
83343
Expiration:
12 months from the date of shipment when stored properly.