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Anti-Phospho-ATF2-T69/T71 Antibody
Catalog #: 144-50720
Phospho-ATF2-T69/T71 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P15336 |
| Gene Id | 1386 |
| Gene Symbols | ATF2 |
| Protein Name / Synonyms | ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
13- 15kDa/23-24kDa/35-54kDa
Observed MW
68kDa
Immunogen
A synthetic phosphorylated peptide around T69 & T71 of human ATF2 (NP_001871.2).
Modification
Phospho T69/T71
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.