Anti-Phospho-ATRIP (S239) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8WXE1
Gene Id	84126
Gene Symbols	ATRIP
Protein Name / Synonyms	Phospho-ATRIP(S239)
Clonality	Polyclonal
Preparation	This ATRIP Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S239 of human ATRIP.
Concentration (lot specific)	0.360 mg/ml
Recommended Applications	Dot Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Specificity

Predicted Reactivity

Monkey

Other Names

ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

NCBI Accession #

NP_001257951.1;NP_001257952.1;NP_115542.2;NP_569055.1

Other Accession #

Q9N077; NP_115542.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

85838

Recommended Dilutions

DB: 1:500

Dot blot analysis of Phospho-ATRIP-S239 Antibody Phospho-specific Pab (Cat# 102-12767) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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