Anti-Phospho-BRAF (S445) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15056
Gene Id	673
Gene Symbols	BRAF
Protein Name / Synonyms	Phospho-BRAF(S445)
Clonality	Polyclonal
Preparation	This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S445 of human BRAF.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Dot Blotting
Research Area	Cardiovascular Disease, Cancer, Ras/Rap Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.

Specificity

Predicted Reactivity

Mouse, Chicken

Other Names

BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1

NCBI Accession #

NP_004324.2

Other Accession #

P28028; Q04982

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

84437

Recommended Dilutions

DB: 1:500

Dot blot analysis of anti-BRAF-pS445 Phospho-specific Pab (Cat# 102-15418) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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