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Anti-Phospho-CBX3-S83 Antibody
Catalog #: 144-50781
Phospho-CBX3-S83 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q13185 |
| Gene Id | 11335 |
| Gene Symbols | CBX3 |
| Protein Name / Synonyms | CBX3, HECH, HP1-GAMMA, HP1Hs-gamma, chromobox 3 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
20kDa
Observed MW
21kDa
Immunogen
A phospho specific peptide corresponding to residues surrounding S83 of human CBX3
Modification
Phospho S83
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.