Anti-Phospho-EIF4EBP1 (S111) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q13541\|Q60876\|Q62622\|NP_004086
Gene Id	1978
Gene Symbols	EIF4EBP1
Protein Name / Synonyms	Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1
Clonality	Polyclonal
Clone	RB13351
Isotype	Kappa, Rabbit
Recommended Applications	Dot Blotting
Research Area	mTOR Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of EIF4EBP1 with eIF4E inhibits complex assembly and represses translation. EIF4EBP1 is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Other Information

NCBI Accession #

NP_004086.1

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

12580

Antigen Source

Human

Images

DB (1:500)

Dot blot analysis of anti-EIF4EBP1-pS111 Phospho-specific Pab (RB13351) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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