3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-Phospho-EIF4G1-S1108 Antibody
Catalog #: 144-50779
Phospho-EIF4G1-S1108 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q04637 |
| Gene Id | 1981 |
| Gene Symbols | EIF4G1 |
| Protein Name / Synonyms | EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18, eukaryotic translation initiation factor 4 gamma 1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
154kDa/158kDa/166kDa/171kDa/175kDa/176kDa
Observed MW
250kDa
Immunogen
A synthetic phosphorylated peptide around S1108 of human EIF4G1 (NP_001181875.1).
Modification
Phospho S1108
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.