Phospho-Jak1-Y1022/1023 pAb
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P23458 |
| Gene Id | 3716 |
| Gene Symbols | JAK1 |
| Protein Name / Synonyms | JAK1, JAK1A, JAK1B, JTK3, Janus kinase 1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Inflammation, JAK/STAT Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
133kDa
Observed MW
130kDa
Immunogen
A phospho specific peptide corresponding to residues surrounding Y1022/1023 of human JAK1
Modification
Phospho Y1022/1023
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.