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Anti-Phospho-PRKCQ-T538 Antibody
Catalog #: 144-50780
Phospho-PRKCQ-T538 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q04759 |
| Gene Id | 5588 |
| Gene Symbols | PRKCQ |
| Protein Name / Synonyms | PRKCQ, PRKCT, nPKC-theta, protein kinase C theta |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
67kDa/74kDa/81kDa
Observed MW
98kDa
Immunogen
A synthetic phosphorylated peptide around T538 of human PRKCQ (NP_006248.1).
Modification
Phospho T538
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.