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Anti-Phospho-PTK2-Y576/577 Antibody
Catalog #: 144-50727
Phospho-PTK2-Y576/577 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q05397 |
| Gene Id | 5747 |
| Gene Symbols | PTK2 |
| Protein Name / Synonyms | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, focal adhesion kinase 1 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
39kDa/48kDa/63kDa/99kDa/114kDa/119kDa/120kDa
Observed MW
130kDa
Immunogen
A synthetic phosphorylated peptide around Y576 & Y577 of human PTK2 (NP_722560.1).
Modification
Phospho Y576/577
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.