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Anti-Phospho-SNCA-S129 Antibody
Catalog #: 144-50697
Phospho-SNCA-S129 pAb
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P37840 |
| Gene Id | 6622 |
| Gene Symbols | SNCA |
| Protein Name / Synonyms | SNCA, NACP, PARK1, PARK4, PD1, alpha-synuclein |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
11kDa/13kDa/14kDa
Observed MW
20kDa
Immunogen
A phospho specific peptide corresponding to residues surrounding S129 of human SNCA
Modification
Phospho S129
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.