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Anti-Phospho-STK11-T189 Antibody
Catalog #: 144-50603
Phospho-STK11-T189 Polyclonal Antibody
Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q15831 |
| Gene Id | 6794 |
| Gene Symbols | STK11 |
| Protein Name / Synonyms | STK11, LKB1, PJS, hLKB1, serine/threonine kinase 11 |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Cancer, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Background
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Dilutions
WB 1:500 - 1:2000
Format
Calculated MW
45kDa/48kDa
Observed MW
54kDa
Immunogen
A phospho specific peptide corresponding to residues surrounding T189 of human STK11
Modification
Phospho T189
Storage
-20°C
Images
Western blot analysis of extracts of A431 cells, using Phospho-STK11-T189 antibody (144-50603) at 1:1000 dilution. A431 cells were treated by 10% FBS for after serum-starvation overnight.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.
Expiration:
12 months from the date of shipment when stored properly.