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Anti-Phospho-TSC2 (T1462) Antibody
Catalog #: 102-25496
Rabbit Anti-Phospho-TSC2(T1462) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49815|Q61037|P49816 |
| Gene Id | 7249 |
| Gene Symbols | TSC2 |
| Protein Name / Synonyms | Tuberin, Tuberous sclerosis 2 protein, TSC2, TSC4 |
| Clonality | Polyclonal |
| Clone | RB13340 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Dot Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
Other Information
NCBI Accession #
NP_000539.2;NP_001070651.1;NP_001107854.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
200608
Antigen Source
Human
Images
DB (1:500)
Dot blot analysis of anti-TSC2-pT1462 Phospho-specific Pab (RB13340) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.