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Anti-pig/Rabbit/Cow/Zebrafish TIMP2 Antibody, Sodium Azide Free
Catalog #: 188-11113-SAF
Mouse anti-Human/Mouse/Rat/Guinea pig/Rabbit/Cow/Zebrafish TIMP2 Antibody [Sodium Azide Free]
Product Description
Specifications
| Size | 100 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Mouse |
| Accession Number | P16035 |
| Gene Id | 7077 |
| Gene Symbols | TIMP2 |
| Protein Name / Synonyms | Metalloproteinase inhibitor 2 (CSC-21K) (Tissue inhibitor of metalloproteinases 2) (TIMP-2) |
| Immunogen | Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody. |
| Isotype | Kappa, IgG2a |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 1 mg/ml in 1X PBS, BSA free, sodium azide free |
| Recommended Applications | IHC (FFPE): 0.5-1ug/ml for 30 min at RT Western Blotting: 0.5-1ug/ml IF: 1-2ug/ml |
| Domain / Region / Terminus | Cytoplasmic, cell surface, secreted |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Description
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Storage
Store the TIMP-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.