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Anti-PKC delta (N-term) Antibody
Catalog #: 102-17071
Rabbit Anti-Human PKC delta (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q05655 |
| Gene Id | 5580 |
| Gene Symbols | PRKCD |
| Protein Name / Synonyms | PKC delta (N-term) |
| Clonality | Polyclonal |
| Preparation | This PKC delta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the N-terminal region of human PKC delta. |
| Concentration (lot specific) | 1.430 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation, PKC Signaling, Autoimmune Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC delta is one of the PKC family members, and may play a role in antigen-dependent control of B-cell function.
Specificity
Other Names
PRKCD; Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta
NCBI Accession #
NP_006245.2;NP_997704.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
77505
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of PKC delta (arrow) using rabbit polyclonal PKC delta Antibody (N-term) (Cat# 102-17071). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRKCD gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.