Anti-PNKP (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q96T60
Gene Id	11284
Gene Symbols	PNKP
Protein Name / Synonyms	PNKP (N-term)
Clonality	Polyclonal
Preparation	This PNKP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the N-terminal region of human PNKP.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.

Specificity

Other Names

PNKP; Bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase; Polynucleotide 3'-phosphatase; 2'(3')-polynucleotidase; Polynucleotide 5'-hydroxyl-kinase

NCBI Accession #

NP_009185.2

Other Accession #

NP_009185.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

57076

Recommended Dilutions

WB: 1:1000

	PNKP Antibody (N-term) (Cat# 102-12318) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PNKP antibody detected the PNKP protein (arrow).
	Western blot analysis of PNKP (arrow) using rabbit polyclonal PNKP Antibody (N-term) (Cat# 102-12318). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PNKP gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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