RayBiotech

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ISO 13485:2016 cGMP

Anti-POGLUT1 Antibody

Catalog #: 144-65126

POGLUT1 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesMouse, Rat
Host SpeciesRabbit
Accession Number
Q8NBL1
Gene Id
56983
Gene Symbols
POGLUT1
Protein Name / Synonyms
C3orf9, CLP46, KDELCL1, KTELC1, LGMD2Z, MDS010, MDSRP, Rumi, hCLP46
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IF
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
Observed MW
46kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.