RayBiotech

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770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-POLG2 Antibody

Catalog #: 144-66208

POLG2 pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman, Mouse, Rat
Host SpeciesRabbit
Accession Number
Q9UHN1
Gene Id
11232
Gene Symbols
POLG2
Protein Name / Synonyms
POLG2, HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB, DNA polymerase gamma 2, accessory subunit
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting, IHC, IF
Shipping TypeBlue ice
Storage-20°C

Description

Background

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:10 - 1:100

Format

Calculated MW
54kDa
Observed MW
55kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of human POLG2 (NP_009146.2).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.